Abstract # 2077 MRI Distortion Correction for Submillimeter-Precision Functional Proton Radiosurgergy

Presenter: Schulte, Reinhard

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In preparation of a proton radiosurgery program for functional brain disorders and epilepsy, we are performing studies to define and improve the accuracy of MRI-based stereotactic localization of intracranial targets. MRI localization is not without problems since it has a poor geometric fidelity [1]. In this report, we summarize the methods and results of MRI-based stereotactic localization studies in a phantom performed in comparison to precision dimensional inspection by a metrology laboratory. The two aims of this work were 1. To quantify the typical errors involved in a stereotactic localization procedure based on MRI. 2. To find ways to minimize these errors. Possible ways to minimize the distortion errors inherent in MRI include - Use of a MRI-compatible stereotactic frame. - Use of all available internal correction methods provided by the manufacturer of the MRI scanner. - Use of a scanner sequence that is less prone to distortion. - Use a specially developed correction procedure for distortions introduced by gradient nonlinearities based on the scan of an oil-filled cubic phantom.

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